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SPRY2 Antikörper

Dieses Anti-SPRY2-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von SPRY2 in WB und IHC. Geeignet für Human.
Produktnummer ABIN7270554

Kurzübersicht für SPRY2 Antikörper (ABIN7270554)

Target

Alle SPRY2 Antikörper anzeigen
SPRY2 (Sprouty Homolog 2 (SPRY2))

Reaktivität

  • 41
  • 24
  • 15
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 45
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 47
  • 3
Monoklonal

Konjugat

  • 41
  • 3
  • 2
  • 2
  • 1
  • 1
Dieser SPRY2 Antikörper ist unkonjugiert

Applikation

  • 42
  • 23
  • 22
  • 13
  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Verwendungszweck

    Sprouty 2 Rabbit mAb

    Kreuzreaktivität

    Human, Ratte

    Produktmerkmale

    Monoclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    A synthesized peptide derived from human Sprouty 2

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    SPRY2 (Sprouty Homolog 2 (SPRY2))

    Andere Bezeichnung

    SPRY2

    Hintergrund

    This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008],IGAN3, hSPRY2,Angiogenesis,Cardiovascular,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Mesenchymal Stem Cells,Neuroscience,Signal Transduction,Stem Cells,SPRY2

    Molekulargewicht

    42kDa

    Gen-ID

    10253

    UniProt

    O43597

    Pathways

    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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