SPIRE2 Antikörper (AA 1-190)

Produktnummer ABIN7270538

Der Kaninchen Polyklonal anti-SPIRE2 Antikörper wird verwendet zum Nachweis von SPIRE2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für SPIRE2 Antikörper (AA 1-190) (ABIN7270538)

Target: SPIRE2 (Spire Homolog 2 (SPIRE2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPIRE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPIRE2 Antikörper

Bindungsspezifität: AA 1-190

Verwendungszweck: SPIRE2 Rabbit pAb

Sequenz: MARAGSCGGA AAGAGRPEPW ELSLEEVLKA YEQPLNEEQA WAVCFQGCRG LRGSPGRRLR DTGDLLLRGD GSVGAREPEA AEPATMVVPL ASSEAQTVQS LGFAIYRALD WGLDESEERE LSPQLERLID LMANNDSEDS GCGAADEGYG GPEEEEEAEG VPRSVRTFAQ AMRLCAARLT DPRGAQAHYQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human SPIRE2 (NP_115827.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPIRE2

Target: SPIRE2 (Spire Homolog 2 (SPIRE2))

Andere Bezeichnung: SPIRE2

Hintergrund: Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage.,SPIRE2,Spir-2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SPIRE2

Molekulargewicht: 65kDa/74kDa/79kDa

Gen-ID: 84501

UniProt: Q8WWL2