SP1 Antikörper (AA 420-620)

Produktnummer ABIN7270506

Dieses Anti-SP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SP1 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für SP1 Antikörper (AA 420-620) (ABIN7270506)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SP1 Antikörper

Bindungsspezifität: AA 420-620

Verwendungszweck: SP1 Rabbit pAb

Sequenz: LSGQTFTTQA ISQETLQNLQ LQAVPNSGPI IIRTPTVGPN GQVSWQTLQL QNLQVQNPQA QTITLAPMQG VSLGQTSSSN TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGT SGIQVHPIQG LPLAIANAPG DHGAQLGLHG AGGDGIHDDT AGGEEGENSP DAQPQAGRRT RREACTCPYC KDSEGRGSGD P

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human SP1 (NP_612482.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Andere Bezeichnung: SP1

Hintergrund: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.,SP1,Epigenetics & Nuclear Signaling,Transcription Factors,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,Neuroscience,Neurodegenerative Diseases,Stem Cells,SP1

Molekulargewicht: 75kDa/79kDa/80kDa

Gen-ID: 6667

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction