SETD7 Antikörper
Kurzübersicht für SETD7 Antikörper (ABIN7270261)
Target
Alle SETD7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SETD7 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human SETD7
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Isotyp
- IgG
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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibody
SETD7 Reaktivität: Human, Ratte, Affe WB, ELISA, IHC Wirt: Maus Monoclonal 3D6G11 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 Reaktivität: Human, Ratte, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 1B3B8 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 5B4 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 159-189) antibodySETD7 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2763 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 Reaktivität: Human, Maus WB, FACS Wirt: Maus Monoclonal 2E3 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-218) antibodySETD7 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 Reaktivität: Human WB, ELISA, FACS, IF, ICC Wirt: Maus Monoclonal s4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (C-Term) antibodySETD7 Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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Andere Bezeichnung
- SETD7
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Hintergrund
- Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.,KMT7, SET7, SET7/9, SET9,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Methylation,Epigenetics & Nuclear Signaling,SETD7
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Molekulargewicht
- 41kDa
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Gen-ID
- 80854
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UniProt
- Q8WTS6
Target
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