SELM Antikörper (AA 50-130)

Produktnummer ABIN7270195

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SELM in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SELM Antikörper (AA 50-130) (ABIN7270195)

Target: SELM (Selenoprotein M (SELM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SELM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SELM Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: SELENOM Rabbit pAb

Sequenz: LNRLKEVKAF VTQDIPFYHN LVMKHLPGAD PELVLLGRRY EELERIPLSE MTREEINALV QELGFYRKAA PDAQVPPEYV W

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SELENOM (NP_536355.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SELM

Target: SELM (Selenoprotein M (SELM))

Andere Bezeichnung: SELENOM

Hintergrund: The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.,SELENOM;SELM;SEPM,SELENOM

Molekulargewicht: 16kDa

Gen-ID: 140606

UniProt: Q8WWX9