RHBDD1 Antikörper (AA 206-315)

Produktnummer ABIN7269978

Dieses Anti-RHBDD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RHBDD1 in WB und IF. Geeignet für Human.

Kurzübersicht für RHBDD1 Antikörper (AA 206-315) (ABIN7269978)

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHBDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RHBDD1 Antikörper

Bindungsspezifität: AA 206-315

Verwendungszweck: RHBDD1 Rabbit pAb

Sequenz: TQGPLKKIME ACAGGFSSSV GYPGRQYYFN SSGSSGYQDY YPHGRPDHYE EAPRNYDTYT AGLSEEEQLE RALQASLWDR GNTRNSPPPY GFHLSPEEMR RQRLHRFDSQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-315 of human RHBDD1 (NP_115652.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RHBDD1

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Andere Bezeichnung: RHBDD1

Hintergrund: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.,RHBDD1,RRP4,Cell Biology & Developmental Biology,Apoptosis,RHBDD1

Molekulargewicht: 12kDa/35kDa

Gen-ID: 84236

UniProt: Q8TEB9