Reticulon 3 Antikörper (C-Term)
Kurzübersicht für Reticulon 3 Antikörper (C-Term) (ABIN7269929)
Target
Alle Reticulon 3 (RTN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- RTN3 Rabbit pAb
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Sequenz
- YKSVIQAVQK SEEGHPFKAY LDVDITLSSE AFHNYMNAAM VHINRALKLI IRLFLVEDLV DSLKLAVFMW LMTYVGAVFN GITLLILAEL LIFSVPIVYE KYKTQIDHYV GIARDQTKSI VEKIQAKLPG IAKKKAE
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RTN3 (NP_006045.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Reticulon 3 (RTN3)
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Andere Bezeichnung
- RTN3
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Hintergrund
- This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.,RTN3,ASYIP,HAP,NSPL2,NSPLII,RTN3-A1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,RTN3
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Molekulargewicht
- 23kDa/25kDa/26kDa/27kDa/100kDa/110kDa/112kDa
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Gen-ID
- 10313
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UniProt
- O95197
Target
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