Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) Antikörper

Produktnummer ABIN7269877

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Ras-Related C3 Botulinum Toxin Substrate 1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) Antikörper (ABIN7269877)

Target: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: pSer71

Verwendungszweck: Phospho-Rac1/Cdc42-S71 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Andere Bezeichnung: CDC42/RAC1

Hintergrund: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013],CDC42Hs, G25K, TKS,CDC42/RAC1

Molekulargewicht: 24kDa

Gen-ID: 998, 5879

UniProt: P60953, P63000