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RSAD2 Antikörper (AA 42-361)

RSAD2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7269832
  • Target Alle RSAD2 Antikörper anzeigen
    RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-361
    Reaktivität
    • 35
    • 27
    • 21
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 31
    • 5
    • 1
    Kaninchen
    Klonalität
    • 32
    • 5
    Polyklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RSAD2 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 13
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    RSAD2 Rabbit pAb
    Sequenz
    LATKRRKQQL VLRGPDETKE EEEDPPLPTT PTSVNYHFTR QCNYKCGFCF HTAKTSFVLP LEEAKRGLLL LKEAGMEKIN FSGGEPFLQD RGEYLGKLVR FCKVELRLPS VSIVSNGSLI RERWFQNYGE YLDILAISCD SFDEEVNVLI GRGQGKKNHV ENLQKLRRWC RDYRVAFKIN SVINRFNVEE DMTEQIKALN PVRWKVFQCL LIEGENCGED ALREAERFVI GDEEFERFLE RHKEVSCLVP ESNQKMKDSY LILDEYMRFL NCRKGRKDPS KSILDVGVEE AIKFSGFDEK MFLKRGGKYI WSKADLKLDW
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 42-361 of human RSAD2 (NP_542388.2).
    Isotyp
    IgG
    Top Product
    Discover our top product RSAD2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
    Andere Bezeichnung
    RSAD2 (RSAD2 Produkte)
    Synonyme
    CIG6 antikoerper, RSAD2 antikoerper, 2510004L01Rik antikoerper, cig33 antikoerper, cig5 antikoerper, vig1 antikoerper, Vig1 antikoerper, Best5 antikoerper, si:ch211-276e8.2 antikoerper, zgc:112342 antikoerper, viperin antikoerper, rsad2 antikoerper, radical S-adenosyl methionine domain containing 2 antikoerper, viperin antikoerper, RSAD2 antikoerper, Rsad2 antikoerper, rsad2 antikoerper, vig1 antikoerper
    Hintergrund
    Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV, hepatitis C virus (HCV, west Nile virus (WNV, dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV, zika virus, and human immunodeficiency virus (HIV-1. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR-mediated GATA3 activation and optimal T-helper 2 (Th2 cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,RSAD2,2510004L01Rik,cig33,cig5,vig1,Immunology & Inflammation,RSAD2
    Molekulargewicht
    42kDa
    Gen-ID
    91543
    UniProt
    Q8WXG1
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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