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Protein Virilizer Homolog (VIRMA) (AA 1400-1700) Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7269712

Kurzübersicht für Protein Virilizer Homolog (VIRMA) (AA 1400-1700) Antikörper (ABIN7269712)

Target

Protein Virilizer Homolog (VIRMA)

Reaktivität

Human

Wirt

  • 3
Kaninchen

Klonalität

  • 3
Polyklonal

Konjugat

  • 3
Unkonjugiert

Applikation

  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 1
    • 1
    AA 1400-1700

    Verwendungszweck

    KIAA1429 Rabbit pAb

    Sequenz

    FMRQILNSDT IGCCGDDNGL MEVEGAHTSR TMSINAAELK QLLQSKEESP ENLFLELEKL VLEHSKDDDN LDSLLDSVVG LKQMLESSGD PLPLSDQDVE PVLSAPESLQ NLFNNRTAYV LADVMDDQLK SMWFTPFQAE EIDTDLDLVK VDLIELSEKC CSDFDLHSEL ERSFLSEPSS PGRTKTTKGF KLGKHKHETF ITSSGKSEYI EPAKRAHVVP PPRGRGRGGF GQGIRPHDIF RQRKQNTSRP PSMHVDDFVA AESKEVVPQD GIPPPKRPLK VSQKISSRGG FSGNRGGRGA F

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human KIAA1429 (NP_056311.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Protein Virilizer Homolog (VIRMA)

    Andere Bezeichnung

    VIRMA

    Hintergrund

    Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA.,KIAA1429,MSTP054,fSAP121,VIRMA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,VIRMA

    Molekulargewicht

    128kDa/154kDa/201kDa/202kDa

    Gen-ID

    25962

    UniProt

    Q69YN4
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