POGLUT1 Antikörper (AA 160-280)

Produktnummer ABIN7269673

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch POGLUT1 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für POGLUT1 Antikörper (AA 160-280) (ABIN7269673)

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POGLUT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-POGLUT1 Antikörper

Bindungsspezifität: AA 160-280

Verwendungszweck: POGLUT1 Rabbit pAb

Sequenz: MYPAWTFWEG GPAVWPIYPT GLGRWDLFRE DLVRSAAQWP WKKKNSTAYF RGSRTSPERD PLILLSRKNP KLVDAEYTKN QAWKSMKDTL GKPAAKDVHL VDHCKYKYLF NFRGVAASFR F

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POGLUT1

Target: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Andere Bezeichnung: POGLUT1

Hintergrund: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],C3orf9,CLP46,KDELCL1,KTELC1,LGMD2Z,MDS010,MDSRP,Rumi,hCLP46,POGLUT1,Cell Biology & Developmental Biology,POGLUT1

Gen-ID: 56983

UniProt: Q8NBL1

Pathways: Notch Signalweg