PRNP Antikörper (AA 23-230)

Produktnummer ABIN7269516

Dieses Anti-PRNP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRNP in WB und IHC. Geeignet für Human.

Kurzübersicht für PRNP Antikörper (AA 23-230) (ABIN7269516)

Target: PRNP (Prion Protein (PRNP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: KO Validated

Produktdetails anti-PRNP Antikörper

Bindungsspezifität: AA 23-230

Verwendungszweck: [KO Validated] Prion Protein Rabbit pAb

Sequenz: KKRPKPGGWN TGGSRYPGQG SPGGNRYPPQ GGGGWGQPHG GGWGQPHGGG WGQPHGGGWG QPHGGGWGQG GGTHSQWNKP SKPKTNMKHM AGAAAAGAVV GGLGGYMLGS AMSRPIIHFG SDYEDRYYRE NMHRYPNQVY YRPMDEYSNQ NNFVHDCVNI TIKQHTVTTT TKGENFTETD VKMMERVVEQ MCITQYERES QAYYQRGS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-230 of human Prion Protein (NP_001073592.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRNP

Target: PRNP (Prion Protein (PRNP))

Andere Bezeichnung: PRNP

Hintergrund: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.,PRNP,ASCR,AltPrP,CD230,CJD,GSS,KURU,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,p27-30,Immunology & Inflammation,CD markers,Neuroscience,Neurodegenerative Diseases,Stem Cells,Hematopoietic Progenitors,PRNP

Molekulargewicht: 8kDa/26kDa/27kDa

Gen-ID: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation