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C14orf166 Antikörper (AA 151-244) (Biotin)

C14orf166 Reaktivität: Human IHC (p), ELISA, IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN717418
  • Target Alle C14orf166 Antikörper anzeigen
    C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))
    Bindungsspezifität
    • 14
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 151-244
    Reaktivität
    • 32
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 27
    • 5
    Kaninchen
    Klonalität
    • 27
    • 5
    Polyklonal
    Konjugat
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C14orf166 Antikörper ist konjugiert mit Biotin
    Applikation
    • 17
    • 13
    • 13
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RLLM1/C14orf166
    Isotyp
    IgG
    Top Product
    Discover our top product C14orf166 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))
    Andere Bezeichnung
    RLLM1 (C14orf166 Produkte)
    Synonyme
    CGI99 antikoerper, CLE antikoerper, CLE7 antikoerper, LCRP369 antikoerper, RLLM1 antikoerper, C14orf166 antikoerper, C10H14orf166 antikoerper, RNA transcription, translation and transport factor antikoerper, chromosome 5 C14orf166 homolog antikoerper, RNA transcription, translation and transport factor S homeolog antikoerper, zgc:56576 antikoerper, RTRAF antikoerper, C5H14orf166 antikoerper, rtraf.S antikoerper, zgc:56576 antikoerper
    Hintergrund

    Synonyms: CGI 99, CGI99, CLE, Homeobox prox 1, RLLM1, Chromosome 14 open reading frame 166, CLE7, LCRP369, RLL mot containing 1, CN166_HUMAN.

    Background: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

    Gen-ID
    51637
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