PGC1 alpha + beta Antikörper

Produktnummer ABIN7269258

Produktdetails

Target: PGC1 alpha + beta

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PGC1α/β Rabbit mAb

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human PGC1alpha/beta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: PGC1 alpha + beta

Andere Bezeichnung: PGC1alpha/beta

Synonyme: LEM6 antikoerper, PGC-1(alpha) antikoerper, PGC-1v antikoerper, PGC1 antikoerper, PGC1A antikoerper, PPARGC1 antikoerper, A830037N07Rik antikoerper, ENSMUSG00000079510 antikoerper, Gm11133 antikoerper, PGC-1 antikoerper, Pgc-1alpha antikoerper, Pgc1 antikoerper, Pgco1 antikoerper, Ppargc1 antikoerper, PPARG coactivator 1 alpha antikoerper, peroxisome proliferative activated receptor, gamma, coactivator 1 alpha antikoerper, PPARGC1A antikoerper, Ppargc1a antikoerper

Hintergrund: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.,LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1A,PPARGC1,ERRL1,PERC,PGC-1(beta),PGC1B,PGC1α/β

Molekulargewicht: 113kDa

Gen-ID: 10891, 133522

UniProt: Q9UBK2, Q86YN6