PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) Antikörper

Produktnummer ABIN7269163

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch PAK4/PAK5/PAK6 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) Antikörper (ABIN7269163)

Target: PAK4/PAK5/PAK6

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: pSer474, pSer560, pSer602

Verwendungszweck: Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S474 of human PAK4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: PAK4/PAK5/PAK6

Hintergrund: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],PAK4/PAK5/PAK6

Molekulargewicht: 64, 80, 75 kDa

Gen-ID: 10298, 57144, 56924