P-Cadherin Antikörper (AA 24-350)

Produktnummer ABIN7269142

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch P-Cadherin in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für P-Cadherin Antikörper (AA 24-350) (ABIN7269142)

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-P-Cadherin Antikörper

Bindungsspezifität: AA 24-350

Verwendungszweck: CDH3 Rabbit pAb

Sequenz: SEPCRAVFRE AEVTLEAGGA EQEPGQALGK VFMGCPGQEP ALFSTDNDDF TVRNGETVQE RRSLKERNPL KIFPSKRILR RHKRDWVVAP ISVPENGKGP FPQRLNQLKS NKDRDTKIFY SITGPGADSP PEGVFAVEKE TGWLLLNKPL DREEIAKYEL FGHAVSENGA SVEDPMNISI IVTDQNDHKP KFTQDTFRGS VLEGVLPGTS VMQVTATDED DAIYTYNGVV AYSIHSQEPK DPHDLMFTIH RSTGTISVIS SGLDREKVPE YTLTIQATDM DGDGSTTTAV AVVEILDAND NAPMFDPQKY EAHVPENAVG HEVQRLT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-350 of human CDH3 (NP_001784.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3

Hintergrund: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).,CDH3,CDHP,HJMD,PCAD,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,Neuroscience,CDH3

Molekulargewicht: 86kDa/91kDa

Gen-ID: 1001

UniProt: P22223