OTX2 Antikörper

Produktnummer ABIN7269116

Der Kaninchen Monoklonal Anti-OTX2-Antikörper wurde für WB validiert. Er ist geeignet, OTX2 in Proben von Human zu detektieren.

Kurzübersicht für OTX2 Antikörper (ABIN7269116)

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser OTX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OTX2 Antikörper

Verwendungszweck: OTX2 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human OTX2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Andere Bezeichnung: OTX2

Hintergrund: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],CPHD6, MCOPS5,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neuroscience,Stem Cells,Transcription Factors,OTX2

Molekulargewicht: 32kDa

Gen-ID: 5015

UniProt: P32243

Pathways: Dopaminergic Neurogenesis