Mu Opioid Receptor 1 Antikörper (C-Term)

Produktnummer ABIN7269101

Der Kaninchen Polyklonal Anti-Mu Opioid Receptor 1-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, Mu Opioid Receptor 1 in Proben von Human zu detektieren.

Kurzübersicht für Mu Opioid Receptor 1 Antikörper (C-Term) (ABIN7269101)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mu Opioid Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Mu Opioid Receptor 1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mu Opioid Receptor(MOR) Rabbit pAb

Sequenz: IYVIIKALVT IPETTFQTVS WHFCIALGYT NSCLNPVLYA FLDENFKRCF REFCIPTSSN IEQQNSTRIR QNTRDHPSTA NTVDRTNHQL ENLEAETAPL P

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human Mu Opioid Receptor(MOR) (NP_000905.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Andere Bezeichnung: OPRM1

Hintergrund: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.,OPRM1;LMOR;M-OR-1;MOP;MOR;MOR1;OPRM,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Neuroscience,OPRM1

Molekulargewicht: 10-20kDa/33-55kDa

Gen-ID: 4988

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane