NCAPD2 Antikörper

Produktnummer ABIN7268948

Der Kaninchen Monoklonal anti-NCAPD2 Antikörper wird verwendet zum Nachweis von NCAPD2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für NCAPD2 Antikörper (ABIN7268948)

Target: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NCAPD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NCAPD2 Antikörper

Verwendungszweck: CNAP1 Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human CNAP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NCAPD2

Target: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Andere Bezeichnung: CNAP1

Hintergrund: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.,NCAPD2, CAP-D2, CNAP1, hCAP-D2, condensin complex subunit 1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,CNAP1

Molekulargewicht: 150kDa

Gen-ID: 9918

UniProt: Q15021