NDUFA1 Antikörper

Produktnummer ABIN7268797

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch NDUFA1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NDUFA1 Antikörper (ABIN7268797)

Target: NDUFA1 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NDUFA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NDUFA1 Antikörper

Verwendungszweck: NDUFA1 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of Human NDUFA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NDUFA1

Target: NDUFA1 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 1, 7.5kDa (NDUFA1))

Andere Bezeichnung: NDUFA1

Hintergrund: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.,NDUFA1,CI-MWFE,MWFE,ZNF183,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,NDUFA1

Molekulargewicht: 8kDa

Gen-ID: 4694

UniProt: O15239