Menin Antikörper (AA 266-615)
Kurzübersicht für Menin Antikörper (AA 266-615) (ABIN7268698)
Target
Alle Menin (MEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 266-615
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Verwendungszweck
- Menin Rabbit pAb
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Sequenz
- QKLLWLLYDL GHLERYPMAL GNLADLEELE PTPGRPDPLT LYHKGIASAK TYYRDEHIYP YMYLAGYHCR NRNVREALQA WADTATVIQD YNYCREDEEI YKEFFEVAND VIPNLLKEAA SLLEAGEERP GEQSQGTQSQ GSALQDPECF AHLLRFYDGI CKWEEGSPTP VLHVGWATFL VQSLGRFEGQ VRQKVRIVSR EAEAAEAEEP WGEEAREGRR RGPRRESKPE EPPPPKKPAL DKGLGTGQGA VSGPPRKPPG TVAGTARGPE GGSTAQVPAP AASPPPEGPV LTFQSEKMKG MKELLVATKI NSSAIKLQLT AQSQVQMKKQ KVSTPSDYTL SFLKRQRKGL
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 266-615 of human Menin (NP_000235.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Andere Bezeichnung
- MEN1
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Hintergrund
- This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.,MEN1,MEAI,SCG2,menin,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,MEN1
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Molekulargewicht
- 63kDa/67kDa/68kDa
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Gen-ID
- 4221
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UniProt
- O00255
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Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
Target
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