MTA1 Antikörper (AA 600-700)

Produktnummer ABIN7268485

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MTA1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MTA1 Antikörper (AA 600-700) (ABIN7268485)

Target: MTA1 (Metastasis Associated 1 (MTA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MTA1 Antikörper

Bindungsspezifität: AA 600-700

Verwendungszweck: MTA1 Rabbit pAb

Sequenz: LMPSRGLANH GQARHMGPSR NLLLNGKSYP TKVRLIRGGS LPPVKRRRMN WIDAPDDVFY MATEETRKIR KLLSSSETKR AARRPYKPIA LRQSQALPPR P

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human MTA1 (NP_004680.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MTA1

Target: MTA1 (Metastasis Associated 1 (MTA1))

Andere Bezeichnung: MTA1

Hintergrund: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.,MTA1,Epigenetics & Nuclear Signaling,MTA1

Molekulargewicht: 49kDa/79kDa/80kDa

Gen-ID: 9112

UniProt: Q13330

Pathways: Chromatin Binding