MCAM Antikörper
Kurzübersicht für MCAM Antikörper (ABIN7268460)
Target
Alle MCAM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CD146/MCAM Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human CD146/MCAM
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Andere Bezeichnung
- MCAM
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Hintergrund
- Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.,CD146, MUC18,Cancer,CDs,Cell Adhesion,Cell Adhesion_Cell Adhesion Molecules,Cell Biology & Developmental Biology,Cytoskeleton,Endothelial Progenitors,Immunology & Inflammation,Invasion and Metastasis,Signal Transduction,Stem Cells,MCAM
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Molekulargewicht
- 72kDa
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Gen-ID
- 4162
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UniProt
- P43121
Target
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