MSL1 Antikörper (AA 210-300)

Produktnummer ABIN7268383

Produktdetails anti-MSL1 Antikörper

Target: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Bindungsspezifität: AA 210-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: MSL1 Rabbit pAb

Sequenz: LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MSL1

Target: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Andere Bezeichnung: MSL1 (MSL1 Produkte)

Synonyme: MSL-1 antikoerper, hMSL1 antikoerper, 2810017F12Rik antikoerper, 4121402D02Rik antikoerper, 4930463F05Rik antikoerper, AA682082 antikoerper, Msl-1 antikoerper, male specific lethal 1 homolog antikoerper, male-specific lethal 1 homolog (Drosophila) antikoerper, MSL1 antikoerper, Msl1 antikoerper

Hintergrund: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1

Gen-ID: 339287

UniProt: Q68DK7