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LGI1 Antikörper (AA 301-557)

This anti-LGI1 antibody (ABIN7268237) is a Rabbit Polyclonal antibody detecting LGI1 in WB, IF. Suitable for Human.
Produktnummer ABIN7268237

Quick Overview for LGI1 Antikörper (AA 301-557) (ABIN7268237)

Target

Alle LGI1 Antikörper anzeigen
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität

  • 42
  • 27
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 28
  • 23
Kaninchen

Klonalität

  • 28
  • 23
Polyklonal

Konjugat

  • 23
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LGI1 Antikörper ist unkonjugiert

Applikation

  • 50
  • 24
  • 14
  • 13
  • 13
  • 13
  • 13
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 17
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-557

    Verwendungszweck

    LGI1 Rabbit pAb

    Sequenz

    QLFGGSHIYK RDSFANKFIK IQDIEILKIR KPNDIETFKI ENNWYFVVAD SSKAGFTTIY KWNGNGFYSH QSLHAWYRDT DVEYLEIVRT PQTLRTPHLI LSSSSQRPVI YQWNKATQLF TNQTDIPNME DVYAVKHFSV KGDVYICLTR FIGDSKVMKW GGSSFQDIQR MPSRGSMVFQ PLQINNYQYA ILGSDYSFTQ VYNWDAEKAK FVKFQELNVQ APRSFTHVSI NKRNFLFASS FKGNTQIYKH VIVDLSA

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 301-557 of human LGI1 (NP_005088.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:50 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    Andere Bezeichnung

    LGI1

    Hintergrund

    This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.,LGI1,ADLTE,ADPAEF,ADPEAF,EPITEMPIN,EPT,ETL1,IB1099,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,LGI1

    Molekulargewicht

    33kDa/58kDa/63kDa

    Gen-ID

    9211

    UniProt

    O95970
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