LRRFIP2 Antikörper (AA 150-340)

Produktnummer ABIN7268214

Produktdetails anti-LRRFIP2 Antikörper

Target: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Bindungsspezifität: AA 150-340

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRFIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: LRRFIP2 Rabbit pAb

Sequenz: VIEEQEEQMA EFYRENEEKS KELERQKHMC SVLQHKMEEL KEGLRQRDEL IEKHGLVIIP DGTPNGDVSH EPVAGAITVV SQEAAQVLES AGEGPLDVRL RKLAGEKEEL LSQIRKLKLQ LEEERQKCSR NDGTVGDLAG LQNGSDLQFI EMQRDANRQI SEYKFKLSKA EQDITTLEQS ISRLEGQVLR Y

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-340 of human LRRFIP2 (NP_060194.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LRRFIP2

Target: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Andere Bezeichnung: LRRFIP2 (LRRFIP2 Produkte)

Hintergrund: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.,LRRFIP2,HUFI-2,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Stem Cells,LRRFIP2

Gen-ID: 9209

UniProt: Q9Y608