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Laminin gamma 1 Antikörper (AA 1300-1609)

Der Kaninchen Polyklonal Anti-Laminin gamma 1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Laminin gamma 1 in Proben von Human zu detektieren.
Produktnummer ABIN7268186

Kurzübersicht für Laminin gamma 1 Antikörper (AA 1300-1609) (ABIN7268186)

Target

Alle Laminin gamma 1 (LAMC1) Antikörper anzeigen
Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reaktivität

  • 48
  • 26
  • 21
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 44
  • 9
  • 5
Kaninchen

Klonalität

  • 42
  • 16
Polyklonal

Konjugat

  • 41
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Laminin gamma 1 Antikörper ist unkonjugiert

Applikation

  • 37
  • 29
  • 17
  • 14
  • 11
  • 9
  • 9
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1300-1609

    Verwendungszweck

    LAMC1 Rabbit pAb

    Sequenz

    IDQKLKDYED LREDMRGKEL EVKNLLEKGK TEQQTADQLL ARADAAKALA EEAAKKGRDT LQEANDILNN LKDFDRRVND NKTAAEEALR KIPAINQTIT EANEKTREAQ QALGSAAADA TEAKNKAHEA ERIASAVQKN ATSTKAEAER TFAEVTDLDN EVNNMLKQLQ EAEKELKRKQ DDADQDMMMA GMASQAAQEA EINARKAKNS VTSLLSIIND LLEQLGQLDT VDLNKLNEIE GTLNKAKDEM KVSDLDRKVS DLENEAKKQE AAIMDYNRDI EEIMKDIRNL EDIRKTLPSG CFNTPSIEKP

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1609 of human LAMC1 (NP_002284.3).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

    Andere Bezeichnung

    LAMC1

    Hintergrund

    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma. Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.,LAMC1,LAMB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,Neurodegenerative Diseases,LAMC1

    Molekulargewicht

    177kDa

    Gen-ID

    3915

    UniProt

    P11047
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