KAT6B Antikörper (AA 400-500)

Produktnummer ABIN7268062

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KAT6B in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KAT6B Antikörper (AA 400-500) (ABIN7268062)

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KAT6B Antikörper

Bindungsspezifität: AA 400-500

Verwendungszweck: KAT6B Rabbit pAb

Sequenz: DLDVFKQAQE LSWEKIECES GVEDCGRYPS VIEFGKYEIQ TWYSSPYPQE YARLPKLYLC EFCLKYMKSK NILLRHSKKC GWFHPPANEI YRRKDLSVFE V

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KAT6B

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Andere Bezeichnung: KAT6B

Hintergrund: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.,KAT6B,GTPTS,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6B

Gen-ID: 23522

UniProt: Q8WYB5