IQGAP1 Antikörper (AA 500-750)
Kurzübersicht für IQGAP1 Antikörper (AA 500-750) (ABIN7268020)
Target
Alle IQGAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 500-750
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Verwendungszweck
- IQGAP1 Rabbit pAb
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Sequenz
- ELMKLKAQAH AENNEFITWN DIQACVDHVN LVVQEEHERI LAIGLINEAL DEGDAQKTLQ ALQIPAAKLE GVLAEVAQHY QDTLIRAKRE KAQEIQDESA VLWLDEIQGG IWQSNKDTQE AQKFALGIFA INEAVESGDV GKTLSALRSP DVGLYGVIPE CGETYHSDLA EAKKKKLAVG DNNSKWVKHW VKGGYYYYHN LETQEGGWDE PPNFVQNSMQ LSREEIQSSI SGVTAAYNRE QLWLANEGLI T
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human IQGAP1 (NP_003861.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
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Andere Bezeichnung
- IQGAP1
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Hintergrund
- This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.,IQGAP1,HUMORFA01,SAR1,p195,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,IQGAP1
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Molekulargewicht
- 189kDa
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Gen-ID
- 8826
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UniProt
- P46940
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Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2
Target
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