INPP5E Antikörper (AA 510-630)
Kurzübersicht für INPP5E Antikörper (AA 510-630) (ABIN7267883)
Target
Alle INPP5E Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 510-630
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Verwendungszweck
- INPP5E Rabbit pAb
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Sequenz
- LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
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Andere Bezeichnung
- INPP5E
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Hintergrund
- The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin,INPP5E,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,INPP5E
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Molekulargewicht
- 66kDa/70kDa
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Gen-ID
- 56623
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UniProt
- Q9NRR6
Target
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