IMPDH1 Antikörper (AA 434-563)
Kurzübersicht für IMPDH1 Antikörper (AA 434-563) (ABIN7267878)
Target
Alle IMPDH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 434-563
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Verwendungszweck
- IMPDH1 Rabbit pAb
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Sequenz
- MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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Andere Bezeichnung
- IMPDH1
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Hintergrund
- The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.,IMPDH1;IMPD;IMPD1;IMPDH-I;LCA11;RP10;sWSS2608,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,Neuroscience,IMPDH1
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Molekulargewicht
- 52kDa/54kDa/55kDa/60kDa/63kDa/64kDa
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Gen-ID
- 3614
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UniProt
- P20839
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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