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PLA2G16 Antikörper (AA 68-162)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLA2G16 in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7267786

Kurzübersicht für PLA2G16 Antikörper (AA 68-162) (ABIN7267786)

Target

Alle PLA2G16 Antikörper anzeigen
PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Reaktivität

  • 26
  • 3
  • 1
Human

Wirt

  • 17
  • 7
  • 2
Kaninchen

Klonalität

  • 21
  • 5
Polyklonal

Konjugat

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PLA2G16 Antikörper ist unkonjugiert

Applikation

  • 14
  • 10
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 68-162

    Verwendungszweck

    PLA2G16 Rabbit pAb

    Sequenz

    VAGSDKYQVN NKHDDKYSPL PCSKIIQRAE ELVGQEVLYK LTSENCEHFV NELRYGVARS DQVRDVIIAA SVAGMGLAAM SLIGVMFSRN KRQKQ

    Kreuzreaktivität

    Human

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 68-162 of human PLA2G16 (NP_009000.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

    Andere Bezeichnung

    PLA2G16

    Hintergrund

    Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1 and A2 (PLA2 activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity,catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE, forming N-acylphosphatidylethanolamine (NAPE, which serves as precursor for N-acylethanolamines (NAEs. Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity. Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light. Organelle membrane degradation is probably catalyzed by the phospholipase activity (By similarity.,PLA2G16,AdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,Cancer,Tumor suppressors,PLA2G16

    Molekulargewicht

    18kDa

    Gen-ID

    11145

    UniProt

    P53816

    Pathways

    Inositol Metabolic Process
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