HSPB11 Antikörper

Produktnummer ABIN7267591

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HSPB11 in WB, IF und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HSPB11 Antikörper (ABIN7267591)

Target: HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-HSPB11 Antikörper

Verwendungszweck: HSPB11 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human HSPB11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HSPB11

Target: HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))

Andere Bezeichnung: HSPB11

Hintergrund: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity.,HSPB11,C1orf41,HSPCO34,IFT25,PP25,HSPB11

Molekulargewicht: 16kDa

Gen-ID: 51668

UniProt: Q9Y547