GNRHR Antikörper (AA 200-300)

Produktnummer ABIN7267500

Dieses Anti-GNRHR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GNRHR in WB. Geeignet für Human.

Kurzübersicht für GNRHR Antikörper (AA 200-300) (ABIN7267500)

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GNRHR Antikörper

Bindungsspezifität: AA 200-300

Verwendungszweck: GNRHR Rabbit pAb

Sequenz: CSFSQWWHQA FYNFFTFSCL FIIPLFIMLI CNAKIIFTLT RVLHQDPHEL QLNQSKNNIP RARLKTLKMT VAFATSFTVC WTPYYVLGIW YWFDPEMLNR L

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GNRHR (NP_000397.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GNRHR

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Andere Bezeichnung: GNRHR

Hintergrund: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.,GNRHR,GNRHR1,GRHR,HH7,LHRHR,LRHR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GNRHR

Molekulargewicht: 27kDa/37kDa

Gen-ID: 2798

UniProt: P30968