GNE Antikörper
Kurzübersicht für GNE Antikörper (ABIN7267398)
Target
Alle GNE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- GNE Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of Human GNE.
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Isotyp
- IgG
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anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 1-150) antibody
GNE Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) antibodyGNE Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (C-Term) antibodyGNE Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 580-607), (C-Term) antibodyGNE Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB26213 unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 169-197), (N-Term) antibodyGNE Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB31032 unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (C-Term) antibodyGNE Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 1-110) antibodyGNE Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 1-722) antibodyGNE Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE) (AA 168-197), (N-Term) antibodyGNE Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
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Andere Bezeichnung
- GNE
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Hintergrund
- The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.,GNE,DMRV,GLCNE,IBM2,NM,Uae1,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cardiovascular,Blood,GNE
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Molekulargewicht
- 66kDa/71kDa/78kDa/79kDa/83kDa
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Gen-ID
- 10020
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UniProt
- Q9Y223
Target
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