GPR4 Antikörper (AA 283-362)
Kurzübersicht für GPR4 Antikörper (AA 283-362) (ABIN7267307)
Target
Alle GPR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 283-362
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Verwendungszweck
- GPR4 Rabbit pAb
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Sequenz
- PILYCLVNEG ARSDVAKALH NLLRFLASDK PQEMANASLT LETPLTSKRN STAKAMTGSW AATPPSQGDQ VQLKMLPPAQ
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 283-362 of human GPR4 (NP_005273.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GPR4 (G Protein-Coupled Receptor 4 (GPR4))
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Andere Bezeichnung
- GPR4
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Hintergrund
- Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC, and GNA12/GNA13/Rho pathways. Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway. In the brain may mediate central respiratory sensitivity to CO(2H(+ (By similarity.,GPR4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),GPR4
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Molekulargewicht
- 40kDa
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Gen-ID
- 2828
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UniProt
- P46093
Target
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