Fibrillin 1 Antikörper (AA 360-460)

Produktnummer ABIN7267176

Dieses Anti-Fibrillin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Fibrillin 1 in WB und IF. Geeignet für Human.

Kurzübersicht für Fibrillin 1 Antikörper (AA 360-460) (ABIN7267176)

Target: Fibrillin 1 (FBN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrillin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Fibrillin 1 Antikörper

Bindungsspezifität: AA 360-460

Verwendungszweck: FBN1 Rabbit pAb

Sequenz: CDAGRCWSPG VTVAPEMCPI RATEDFNKLC SVPMVIPGRP EYPPPPLGPI PPVLPVPPGF PPGPQIPVPR PPVEYLYPSR EPPRVLPVNV TDYCQLVRYL C

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-460 of human FBN1 (NP_000129.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Fibrillin 1

Target: Fibrillin 1 (FBN1)

Andere Bezeichnung: FBN1

Hintergrund: This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome.,FBN1,ACMICD,ECTOL1,FBN,GPHYSD2,MASS,MFLS,MFS1,OCTD,SGS,SSKS,WMS,WMS2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,FBN1

Molekulargewicht: 312kDa

Gen-ID: 2200

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom