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FAM107A Antikörper (AA 1-144)

Der Kaninchen Polyklonal Anti-FAM107A-Antikörper wurde für WB validiert. Er ist geeignet, FAM107A in Proben von Human zu detektieren.
Produktnummer ABIN7267100

Kurzübersicht für FAM107A Antikörper (AA 1-144) (ABIN7267100)

Target

Alle FAM107A Antikörper anzeigen
FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reaktivität

  • 25
  • 10
  • 7
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 21
  • 4
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FAM107A Antikörper ist unkonjugiert

Applikation

  • 9
  • 9
  • 7
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 1
    AA 1-144

    Verwendungszweck

    FAM107A Rabbit pAb

    Sequenz

    MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL

    Kreuzreaktivität

    Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human FAM107A (NP_009108.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

    Andere Bezeichnung

    FAM107A

    Hintergrund

    Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.,FAM107A,DRR1,TU3A,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,FAM107A

    Molekulargewicht

    15kDa/17kDa/20kDa

    Gen-ID

    11170

    UniProt

    O95990
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