FAM107A Antikörper (AA 1-144)

Produktnummer ABIN7267100

Der Kaninchen Polyklonal Anti-FAM107A-Antikörper wurde für WB validiert. Er ist geeignet, FAM107A in Proben von Human zu detektieren.

Kurzübersicht für FAM107A Antikörper (AA 1-144) (ABIN7267100)

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM107A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAM107A Antikörper

Bindungsspezifität: AA 1-144

Verwendungszweck: FAM107A Rabbit pAb

Sequenz: MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human FAM107A (NP_009108.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FAM107A

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Andere Bezeichnung: FAM107A

Hintergrund: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.,FAM107A,DRR1,TU3A,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,FAM107A

Molekulargewicht: 15kDa/17kDa/20kDa

Gen-ID: 11170

UniProt: O95990