FAM107A Antikörper (AA 1-144)
Kurzübersicht für FAM107A Antikörper (AA 1-144) (ABIN7267100)
Target
Alle FAM107A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-144
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Verwendungszweck
- FAM107A Rabbit pAb
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Sequenz
- MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human FAM107A (NP_009108.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))
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Andere Bezeichnung
- FAM107A
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Hintergrund
- Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.,FAM107A,DRR1,TU3A,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,FAM107A
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Molekulargewicht
- 15kDa/17kDa/20kDa
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Gen-ID
- 11170
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UniProt
- O95990
Target
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