FBXO8 Antikörper (AA 110-250)
Kurzübersicht für FBXO8 Antikörper (AA 110-250) (ABIN7267096)
Target
Alle FBXO8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 110-250
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Verwendungszweck
- FBXO8 Rabbit pAb
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Sequenz
- GLCKSTWGHC SIYNKNPPLG FSFRKLYMQL DEGSLTFNAN PDEGVNYFMS KGILDDSPKE IAKFIFCTRT LNWKKLRIYL DERRDVLDDL VTLHNFRNQF LPNALREFFR HIHAPEERGE YLETLITKFS HRFCACNPDL M
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human FBXO8 (NP_036312.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- FBXO8 (F-Box Protein 8 (FBXO8))
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Andere Bezeichnung
- FBXO8
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Hintergrund
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008],DC10,FBS,FBX8,FBXO8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,FBXO8
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Molekulargewicht
- 32kDa/37kDa
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Gen-ID
- 26269
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UniProt
- Q9NRD0
Target
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