FBXO8 Antikörper (AA 110-250)

Produktnummer ABIN7267096

Produktdetails anti-FBXO8 Antikörper

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Bindungsspezifität: AA 110-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: FBXO8 Rabbit pAb

Sequenz: GLCKSTWGHC SIYNKNPPLG FSFRKLYMQL DEGSLTFNAN PDEGVNYFMS KGILDDSPKE IAKFIFCTRT LNWKKLRIYL DERRDVLDDL VTLHNFRNQF LPNALREFFR HIHAPEERGE YLETLITKFS HRFCACNPDL M

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human FBXO8 (NP_036312.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FBXO8

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Andere Bezeichnung: FBXO8 (FBXO8 Produkte)

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008],DC10,FBS,FBX8,FBXO8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,FBXO8

Molekulargewicht: 32kDa/37kDa

Gen-ID: 26269

UniProt: Q9NRD0