DIAPH1 Antikörper (AA 1149-1263)
Kurzübersicht für DIAPH1 Antikörper (AA 1149-1263) (ABIN7266750)
Target
Alle DIAPH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 1149-1263
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Verwendungszweck
- [KO Validated] DIAPH1 Rabbit pAb
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Sequenz
- TEEKMRRAKL AKEKAEKERL EKQQKREQLI DMNAEGDETG VMDSLLEALQ SGAAFRRKRG PRQANRKAGC AVTSLLASEL TKDDAMAAVP AKVSKNSETF PTILEEAKEL VGRAS
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1149-1263 of human DIAPH1 (NP_001073280.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
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Andere Bezeichnung
- DIAPH1
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Hintergrund
- This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DIAPH1,DFNA1,DIA1,DRF1,LFHL1,SCBMS,hDIA1,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,DIAPH1
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Molekulargewicht
- 138kDa/140kDa/141kDa
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Gen-ID
- 1729
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UniProt
- O60610
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Pathways
- Sensory Perception of Sound
Target
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