CHORDC1 Antikörper (AA 60-160)
Kurzübersicht für CHORDC1 Antikörper (AA 60-160) (ABIN7266619)
Target
Alle CHORDC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 60-160
-
Verwendungszweck
- CHORDC1 Rabbit pAb
-
Sequenz
- TKGRHNSEKP PEPVKPEVKT TEKKELCELK PKFQEHIIQA PKPVEAIKRP SPDEPMTNLE LKISASLKQA LDKLKLSSGN EENKKEEDND EIKIGTSCKN G
-
Kreuzreaktivität
- Maus
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))
-
Andere Bezeichnung
- CHORDC1
-
Hintergrund
- Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.,CHORDC1,CHP1,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CHORDC1
-
Gen-ID
- 26973
-
UniProt
- Q9UHD1
Target
-