CHORDC1 Antikörper (AA 60-160)

Produktnummer ABIN7266619

Produktdetails anti-CHORDC1 Antikörper

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Bindungsspezifität: AA 60-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHORDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: CHORDC1 Rabbit pAb

Sequenz: TKGRHNSEKP PEPVKPEVKT TEKKELCELK PKFQEHIIQA PKPVEAIKRP SPDEPMTNLE LKISASLKQA LDKLKLSSGN EENKKEEDND EIKIGTSCKN G

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CHORDC1

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Andere Bezeichnung: CHORDC1 (CHORDC1 Produkte)

Hintergrund: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.,CHORDC1,CHP1,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CHORDC1

Gen-ID: 26973

UniProt: Q9UHD1