CRTC2 Antikörper (AA 434-693)

Produktnummer ABIN7266519

Der Kaninchen Polyklonal anti-CRTC2 Antikörper (ABIN7266519) detektiert spezifisch CRTC2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CRTC2 Antikörper (AA 434-693) (ABIN7266519)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRTC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRTC2 Antikörper

Bindungsspezifität: AA 434-693

Verwendungszweck: CRTC2 Rabbit pAb

Sequenz: PLSLLAGPAD ARRSQQQLPK QFSPTMSPTL SSITQGVPLD TSKLSTDQRL PPYPYSSPSL VLPTQPHTPK SLQQPGLPSQ SCSVQSSGGQ PPGRQSHYGT PYPPGPSGHG QQSYHRPMSD FNLGNLEQFS MESPSASLVL DPPGFSEGPG FLGGEGPMGG PQDPHTFNHQ NLTHCSRHGS GPNIILTGDS SPGFSKEIAA ALAGVPGFEV SAAGLELGLG LEDELRMEPL GLEGLNMLSD PCALLPDPAV EESFRSDRLQ

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 434-693 of human CRTC2 (NP_859066.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Andere Bezeichnung: CRTC2

Hintergrund: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.,CRTC2,TORC-2,TORC2,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,CRTC2

Molekulargewicht: 73kDa

Gen-ID: 200186

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis