COX11 Antikörper (AA 140-240)

Produktnummer ABIN7266513

Dieses Anti-COX11-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von COX11 in WB. Geeignet für Human.

Kurzübersicht für COX11 Antikörper (AA 140-240) (ABIN7266513)

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COX11 Antikörper

Bindungsspezifität: AA 140-240

Verwendungszweck: COX11 Rabbit pAb

Sequenz: ENMVPVKDRI IKISFNADVH ASLQWNFRPQ QTEIYVVPGE TALAFYRAKN PTDKPVIGIS TYNIVPFEAG QYFNKIQCFC FEEQRLNPQE EVDMPVFFYI D

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human COX11 (NP_004366.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COX11

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Andere Bezeichnung: COX11

Hintergrund: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.,COX11,COX11P,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COX11

Molekulargewicht: 26kDa/31kDa

Gen-ID: 1353

UniProt: Q9Y6N1

Pathways: Regulation of Carbohydrate Metabolic Process