Coronavirus Spike Glycoprotein Antikörper

Produktnummer ABIN7266506

Der Kaninchen Polyklonal Anti-Coronavirus Spike Glycoprotein-Antikörper wurde für ELISA, WB, IP und IF validiert. Er ist geeignet, Coronavirus Spike Glycoprotein in Proben von SARS Coronavirus-2 (SARS-CoV-2) zu detektieren.

Kurzübersicht für Coronavirus Spike Glycoprotein Antikörper (ABIN7266506)

Target: Coronavirus Spike Glycoprotein (CoV S)

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coronavirus Spike Glycoprotein Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-Coronavirus Spike Glycoprotein Antikörper

Verwendungszweck: SARS-CoV-2 Spike Rabbit pAb

Kreuzreaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of SARS-CoV-2 Spike.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA,1:40000-1:160000,WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Coronavirus Spike Glycoprotein

Target: Coronavirus Spike Glycoprotein (CoV S)

Andere Bezeichnung: Spike

Substanzklasse: Viral Protein

Hintergrund: The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion, Defines the range of the hosts and specificity of the virus, Main component to bind with the neutralizing antibody, Key target for vaccine design, Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.,Spike

Gen-ID: 43740568

UniProt: P0DTC2