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CMKLR1 Antikörper (AA 250-350)

This anti-CMKLR1 antibody (ABIN7266327) is a Rabbit Polyclonal antibody detecting CMKLR1 in WB, IF. Suitable for Human.
Produktnummer ABIN7266327

Kurzübersicht für CMKLR1 Antikörper (AA 250-350) (ABIN7266327)

Target

Alle CMKLR1 Antikörper anzeigen
CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Reaktivität

  • 69
  • 42
  • 24
  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 71
  • 3
  • 2
Kaninchen

Klonalität

  • 69
  • 6
  • 1
Polyklonal

Konjugat

  • 31
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CMKLR1 Antikörper ist unkonjugiert

Applikation

  • 56
  • 26
  • 26
  • 23
  • 20
  • 13
  • 10
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 16
    • 15
    • 9
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-350

    Verwendungszweck

    CMKLR1 Rabbit pAb

    Sequenz

    NRLAKTKKPF KIIVTIIITF FLCWCPYHTL NLLELHHTAM PGSVFSLGLP LATALAIANS CMNPILYVFM GQDFKKFKVA LFSRLVNALS EDTGHSSYPS H

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CMKLR1 (NP_001135815.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

    Andere Bezeichnung

    CMKLR1

    Hintergrund

    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i/G(o and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2, TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis PubMed:27716822. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2 and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.,CMKLR1,CHEMERINR,ChemR23,DEZ,RVER1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,CMKLR1

    Molekulargewicht

    42kDa

    Gen-ID

    1240

    UniProt

    Q99788
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