CCL17 Antikörper (AA 420-500)

Produktnummer ABIN7266299

Der Kaninchen Polyklonal Anti-CCL17-Antikörper wurde für WB und IF validiert. Er ist geeignet, CCL17 in Proben von Human zu detektieren.

Kurzübersicht für CCL17 Antikörper (AA 420-500) (ABIN7266299)

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CCL17 Antikörper

Bindungsspezifität: AA 420-500

Verwendungszweck: ABCD2 Rabbit pAb

Sequenz: TARVYNMFWV FDEVKRGIYK RTAVIQESES HSKNGAKVEL PLSDTLAIKG KVIDVDHGII CENVPIITPA GEVVASRLNF K

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-500 of human ABCD2 (NP_005155.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Andere Bezeichnung: ABCD2

Hintergrund: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.,ABCD2,ABC39,ALDL1,ALDR,ALDRP,hALDR,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ABCD2

Molekulargewicht: 83kDa

Gen-ID: 225

UniProt: Q9UBJ2