Der Kaninchen Polyklonal anti-CLN8 Antikörper (ABIN7266285) detektiert spezifisch CLN8 in WB und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
CLN8
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:300
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
CLN8
(Ceroid-Lipofuscinosis, Neuronal 8 (Epilepsy, Progressive with Mental Retardation) (CLN8))
Andere Bezeichnung
CLN8
Hintergrund
This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain.,CLN8,C8orf61,EPMR,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Neurodegenerative Diseases,CLN8