CERKL Antikörper (AA 359-558)
Kurzübersicht für CERKL Antikörper (AA 359-558) (ABIN7266283)
Target
Alle CERKL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 359-558
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Verwendungszweck
- CERKL Rabbit pAb
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Sequenz
- LAEKYRWMSP NQRRDFAVVK ALAKLKAEDC EISFLPFNSS DDVQERRAQG SPKSDCNDQW QMIQGQFLNV SIMAIPCLCS VAPRGLAPNT RLNNGSMALI IARNTSRPEF IKHLKRYASV KNQFNFPFVE TYTVEEVKVH PRNNTGGYNP EEEEDETASE NCFPWNVDGD LMEVASEVHI RLHPRLISLY GGSMEEMIPK
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Kreuzreaktivität
- Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 359-558 of human CERKL (NP_001025482.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CERKL (Ceramide Kinase-Like (CERKL))
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Andere Bezeichnung
- CERKL
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Hintergrund
- This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.,CERKL,RP26,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,CERKL
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Molekulargewicht
- 19kDa, 24kDa, 42-62kDa
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Gen-ID
- 375298
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UniProt
- Q49MI3
Target
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