CDK1/2/3 (pThr14) Antikörper

Produktnummer ABIN7266234

Der Kaninchen Monoklonal anti-CDK1/2/3 Antikörper (ABIN7266234) detektiert spezifisch CDK1/2/3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CDK1/2/3 (pThr14) Antikörper (ABIN7266234)

Target: CDK1/2/3

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: pThr14

Verwendungszweck: Phospho-CDK1/2/3-T14 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding T14 of human CDK1/2/3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: CDK1/2/3

Andere Bezeichnung: CDK1/CDK2/CDK3

Hintergrund: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],CDC2, CDC28A, P34CDC2,Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G protein signaling,G2/M DNA Damage Checkpoint,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,CDK1/CDK2/CDK3

Molekulargewicht: 34kDa

Gen-ID: 983, 1017, 1018

UniProt: P06493, P24941, Q00526