Cadherin 13 Antikörper

Produktnummer ABIN7265996

Der Kaninchen Monoklonal Anti-Cadherin 13-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Cadherin 13 in Proben von Human zu detektieren.

Kurzübersicht für Cadherin 13 Antikörper (ABIN7265996)

Target: Cadherin 13 (CDH13)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cadherin 13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cadherin 13 Antikörper

Verwendungszweck: Cadherin-13 (CDH13) Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Cadherin-13 (CDH13)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: CDH13

Hintergrund: This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011],CDHH, P105,Calcium Signaling,Cancer,Cell Adhesion,Cell Adhesion_Cadherins,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton,Invasion and Metastasis,Neuroscience,Signal Transduction,CDH13

Molekulargewicht: 105,130kDa

Gen-ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization